Research Stories of Omega 3-6 Balance – How we got to “NIX6 and EAT3“.
The efaeducation website site began long ago as dialog among NIAAA/NIH research scientists in the Laboratory of Membrane Biochemistry and Biophysics. They wanted the public to have easy access to new research stories about essential fatty acids (EFA). Year by year, the data grew into a body of knowledge that now extends far beyond the early ideas about EFA.
No person can ever step into the same river twice – Heraclitus noted that people and their environment constantly change. Life is an interaction of genes with their environment that “surfs” on waves of energy and nutrients, changing from day to day, and differing year to year.

The list below points to evidence that gave insight and understanding about how omega-3 and omega-6 nutrients affect health conditions. Eating balanced omega-3 and omega-6 nutrients controls the balance of n-3 and n-6 highly unsaturated fatty acids (HUFA) stored in our tissues. A simple measure of each food item’s likely impact on your HUFA balance is posted on-line to help you NIX6 and EAT3.research on Omega 3-6 Balance The stored HUFA are precursors of a diverse set of hormones that act on specific receptors that signal in cells throughout the body, linking n-3 and n-6 nutrients to healthy physiology and pathophysiology.

EFA nutrients: Their Diet-Tissue Dynamics

DHA in Developing Brain

DHA and depression

EFA Actions in Psychiatric Disorders

HUFA balance in Eicosanoid Formation & Action

HUFA, Eicosanoids & Cytokines in Immune-Inflammatory Disorders

G-protein coupled Receptors (GPCR) act in Phospholipid Bilayers

Ideas about Cholesterol – Clarifying Evidence

EFA, Seafood, Selenium & Mercury – Clarifying Evidence


revised October, 2017